The use of Fourier Transform Infrared (FTIR) spectroscopy in skin cancer research : a systematic review
Shakya, Bijay Ratna; Shrestha, Pragya; Teppo, Hanna-Riikka; Rieppo, Lassi (2020-07-13)
Bijay Ratna Shakya, Pragya Shrestha, Hanna-Riikka Teppo & Lassi Rieppo (2021) The use of Fourier Transform Infrared (FTIR) spectroscopy in skin cancer research: a systematic review, Applied Spectroscopy Reviews, 56:5, 347-379, DOI: 10.1080/05704928.2020.1791152
This is an Accepted Manuscript version of the following article, accepted for publication in Applied Spectroscopy Reviews: Bijay Ratna Shakya, Pragya Shrestha, Hanna-Riikka Teppo & Lassi Rieppo (2021) The use of Fourier Transform Infrared (FTIR) spectroscopy in skin cancer research: a systematic review, Applied Spectroscopy Reviews, 56:5, 347-379, DOI: 10.1080/05704928.2020.1791152. It is deposited under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
https://creativecommons.org/licenses/by-nc-nd/4.0/
https://urn.fi/URN:NBN:fi-fe2023040535126
Tiivistelmä
Abstract
Skin cancers are one of the most frequently occurring diseases in humans that pose severe health issues. Fourier Transform Infrared (FTIR) spectroscopy in cancer research has gained considerable attention because of its ability to provide biochemical information in addition to being compatible with traditional histopathology. With this review, we aim to identify all skin cancer studies which have been conducted using FTIR spectroscopy and depict different methodologies that have been used to analyze FTIR spectroscopic data of skin cancers. We conducted the systematic review following PRISMA guidelines for which three databases, Scopus, PubMed and Web of Science, were searched from commencement to 16 January 2019. All the studies which used FTIR spectroscopy for skin cancer research were included in the review. A total of 35 studies were found eligible to be included in the review. Of these, 21 studies were based on melanoma, 6 studies on BCC, 2 studies on SCC, and 2 on lymphocytes. The remaining 4 studies aimed to differentiate between various skin cancer types. The potential of FTIR spectroscopy for many relevant aspects of skin cancer research has already been demonstrated, but more work is needed to establish FTIR spectroscopy as a routine method in the field.
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