Efficient regio- and stereoselective access to novel fluorinated β-aminocyclohexanecarboxylates
Kiss, L., Nonn, M., Sillanpää, R., Fustero, S., & Fülöp, F. (2013). Efficient regio- and stereoselective access to novel fluorinated β-aminocyclohexanecarboxylates. Beilstein Journal of Organic Chemistry, 9, 1164-1169. https://doi.org/10.3762/bjoc.9.130
Julkaistu sarjassa
Beilstein Journal of Organic ChemistryPäivämäärä
2013A regio- and stereoselective method has been developed for the synthesis of novel fluorinated 2-aminocyclohexanecarboxylic acid derivatives with the fluorine attached to position 4 of the ring. The synthesis starts from either cis- or trans-β-aminocyclohex-4-enecarboxylic acids and involves regio- and stereoselective transformation of the ring C–C double bond through iodooxazine formation and hydroxylation, followed by hydroxy–fluorine or oxo–fluorine exchange.
Julkaisija
Beilstein - Institut zur Foerderung der Chemischen WissenschaftenISSN Hae Julkaisufoorumista
1860-5397
Alkuperäislähde
http://www.beilstein-journals.org/bjoc/home/home.htmJulkaisu tutkimustietojärjestelmässä
https://converis.jyu.fi/converis/portal/detail/Publication/23006295
Metadata
Näytä kaikki kuvailutiedotKokoelmat
Samankaltainen aineisto
Näytetään aineistoja, joilla on samankaltainen nimeke tai asiasanat.
-
Stereocontrolled synthesis of fluorine-containing piperidine γ-amino acid derivatives
Ouchakour, Lamiaa; Ábrahámi, Renáta A.; Forró, Enikő; Haukka, Matti; Fülöp, Ferenc; Kiss, Lorand (Wiley, 2019)An efficient synthetic approach for the construction of fluorine‐containing piperidine γ‐amino acid derivatives has been developed. The synthetic concept was based on oxidative ring opening of an unsaturated bicyclic ... -
Fluorination of some highly functionalized cycloalkanes: chemoselectivity and substrate dependence
Remete, Attila Márió; Nonn, Melinda; Fustero, Santos; Haukka, Matti; Fülöp, Ferenc; Kiss, Loránd (Beilstein-Institut, 2017)A study exploring the chemical behavior of some dihydroxylated β-amino ester stereo- and regioisomers, derived from unsaturated cyclic β-amino acids is described. The nucleophilic fluorinations involving hydroxy–fluorine ... -
Fluorine-containing functionalized cyclopentene scaffolds through ring contraction and deoxofluorination of various substituted cyclohexenes
Remete, Attila Márió; Nonn, Melinda; Fustero, Santos; Haukka, Matti; Fülöp, Ferenc; Kiss, Lorand (Wiley-VCH, 2018)The fluorination of some highly‐functionalized cyclopentene derivatives, obtained from various substituted cyclohexenes through a ring‐opening/ring‐contraction procedure, has been investigated. The transformations were ... -
Synthesis of novel fluorinated building blocks via halofluorination and related reactions
Remete, Attila Márió; Novák, Tamás T.; Nonn, Melinda; Haukka, Matti; Fülöp, Ferenc; Kiss, Loránd (Beilstein-Institut zur Förderung der Chemischen Wissenschaften, 2020)A study exploring halofluorination and fluoroselenation of some cyclic olefins, such as diesters, imides, and lactams with varied functionalization patterns and different structural architectures is described. The synthetic ... -
A One-Pot Domino Reaction Providing Fluorinated 5,6-Dihydro-1,2-thiazine 1-Oxides from Sulfoximines and 1-Trifluoromethylstyrenes
Wang, Xianliang; Rissanen, Kari; Bolm, Carsten (American Chemical Society (ACS), 2023)N-Trifluoroacetylated (N-TFA) sulfoximines react with 1-trifluoromethylstyrenes in a one-pot domino reaction to give fluorinated 5,6-dihydro-1,2-thiazine 1-oxides in good to high yields. The process involves three sequential ...
Ellei toisin mainittu, julkisesti saatavilla olevia JYX-metatietoja (poislukien tiivistelmät) saa vapaasti uudelleenkäyttää CC0-lisenssillä.