Lung cancer risk in relation to jobs held in a nationwide case-control study in Iran
Hosseini, Bayan; Olsson, Ann; Bouaoun, Liacine; Hall, Amy; Hadji, Maryam; Rashidian, Hamideh; Naghibzadeh-Tahami, Ahmad; Marzban, Maryam; Najafi, Farid; Haghdoost, Ali Akbar; Boffetta, Paolo; Kamangar, Farin; Pukkala, Eero; Etemadi, Arash; Weiderpass, Elisabete; Schüz, Joachim; Zendehdel, Kazem (2022)
Hosseini, Bayan
Olsson, Ann
Bouaoun, Liacine
Hall, Amy
Hadji, Maryam
Rashidian, Hamideh
Naghibzadeh-Tahami, Ahmad
Marzban, Maryam
Najafi, Farid
Haghdoost, Ali Akbar
Boffetta, Paolo
Kamangar, Farin
Pukkala, Eero
Etemadi, Arash
Weiderpass, Elisabete
Schüz, Joachim
Zendehdel, Kazem
2022
Julkaisun pysyvä osoite on
https://urn.fi/URN:NBN:fi:tuni-202212219699
https://urn.fi/URN:NBN:fi:tuni-202212219699
Kuvaus
Peer reviewed
Tiivistelmä
Background: Globally, lung cancer is the most frequent occupational cancer, but the risk associated with the occupations or occupational environment in Iran is not clear. We aimed to assess occupations with the risk of lung cancer. Methods: We used the IROPICAN nationwide case-control study data including 658 incident lung cancer cases and 3477 controls. We assessed the risk of lung cancer in relation to ever working in major groups of International Standard Classification of Occupations, high-risk occupations for lung cancer and duration of employment and lung cancer subtype among construction workers and farmers while controlling for cigarette smoking and opium consumption. We used unconditional regression logistic models to estimate ORs for the association between increased lung cancer risk and occupations. Results: We observed elevated ORs for lung cancer in male construction workers (OR=1.4; 95% CI: 1.0 to 1.8), petroleum industry workers (OR=3.2; 95% CI: 1.1 to 9.8), female farmers (OR=2.6; 95% CI: 1.3 to 5.3) and female bakers (OR=5.5; 95% CI: 1.0 to 29.8). A positive trend by the duration of employment was observed for male construction workers (p< 0.001). Increased risk of squamous cell carcinoma was observed in male construction workers (OR=1.9; 95% CI: 1.2 to 3.0) and female farmers (OR=4.3; 95% CI: 1.1 to 17.2), who also experienced an increased risk of adenocarcinoma (OR=3.8; 95% CI: 1.4 to 9.9). Discussion: Although we observed associations between some occupations and lung cancer consistent with the literature, further studies with larger samples focusing on exposures are needed to better understand the occupational lung cancer burden in Iran.
Kokoelmat
- TUNICRIS-julkaisut [16977]