Dementia prevention : the potential long-term cost-effectiveness of the FINGER prevention program
Wimo, Anders; Handels, Ron; Antikainen, Riitta; Eriksdotter, Maria; Jönsson, Linus; Knapp, Martin; Kulmala, Jenni; Laatikainen, Tiina; Lehtisalo, Jenni; Peltonen, Markku; Sköldunger, Anders; Soininen, Hilkka; Solomon, Alina; Strandberg, Timo; Tuomilehto, Jaakko; Ngandu, Tiia; Kivipelto, Miia (2022-07-16)
Wimo, A, Handels, R, Antikainen, R, et al. Dementia prevention: The potential long-term cost-effectiveness of the FINGER prevention program. Alzheimer's Dement. 2023; 19: 999–1008. https://doi.org/10.1002/alz.12698
© 2022 The Authors. Alzheimer’s & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer’s Association. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
https://creativecommons.org/licenses/by-nc-nd/4.0/
https://urn.fi/URN:NBN:fi-fe20230825107893
Tiivistelmä
Abstract
Introduction: The aim of this study was to estimate the potential cost-effectiveness of the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) program.
Methods: A life-time Markov model with societal perspective, simulating a cohort of people at risk of dementia reflecting usual care and the FINGER program.
Results: Costs were 1,653,275 and 1,635,346 SEK and quality-adjusted life years (QALYs) were 8.636 and 8.679 for usual care and the FINGER program, respectively, resulting in savings of 16,928 SEK (2023 US$) and 0.043 QALY gains per person, supporting extended dominance for the FINGER program. A total of 1623 dementia cases were avoided with 0.17 fewer person-years living with dementia. The sensitivity analysis confirmed the conclusions in most scenarios.
Discussion: The model provides support that programs like FINGER have the potential to be cost-effective in preventing dementia. Results at the individual level are rather modest, but the societal benefits can be substantial because of the large potential target population.
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