Adolescent social functioning deficits in association with adoptive family functioning and genetic risk for schizophrenia spectrum disorders : the Finnish adoptive family study of schizophrenia
Tikkanen, Ville; Siira, Virva; Wahlberg, Karl-Erik; Hakko, Helinä; Myllyaho, Toni; Läksy, Kristian; Roisko, Riikka; Niemelä, Mika; Räsänen, Sami (2022-06-01)
Tikkanen, Ville MA∗; Siira, Virva PhD†; Wahlberg, Karl-Erik PhD∗; Hakko, Helinä PhD‡; Myllyaho, Toni MA∗; Läksy, Kristian MD§; Roisko, Riikka MD‡; Niemelä, Mika PhD‡,∥; Räsänen, Sami MD∗,‡. Adolescent Social Functioning Deficits in Association With Adoptive Family Functioning and Genetic Risk for Schizophrenia Spectrum Disorders: The Finnish Adoptive Family Study of Schizophrenia. The Journal of Nervous and Mental Disease 210(6):p 418-425, June 2022. | DOI: 10.1097/NMD.0000000000001483
© 2022 Wolters Kluwer Health, Inc. This is a non-final version of an article published in final form in Tikkanen, Ville; Siira, Virva; Wahlberg, Karl-Erik; Hakko, Helinä; Myllyaho, Toni; Läksy, Kristian; Roisko, Riikka; Niemelä, Mika; Räsänen, Sami. Adolescent Social Functioning Deficits in Association With Adoptive Family Functioning and Genetic Risk for Schizophrenia Spectrum Disorders: The Finnish Adoptive Family Study of Schizophrenia. The Journal of Nervous and Mental Disease 210(6):p 418-425, June 2022. | DOI: 10.1097/NMD.0000000000001483.
https://rightsstatements.org/vocab/InC/1.0/
https://urn.fi/URN:NBN:fi-fe202301255533
Tiivistelmä
Abstract
Social functioning deficits (SFDs) during adolescence represent potential vulnerability indicators to schizophrenia spectrum disorders, but little is known about how both family environmental and genetic factors contribute to SFDs. The aim of this study was to examine the association of adoptees’ adolescent social functioning with adoptive family functioning and adoptees’ high (HR) or low (LR) genetic risk for schizophrenia spectrum disorders. The present subsample from the nationwide Finnish Adoptive Family Study of Schizophrenia included 88 HR and 83 LR adoptees. Adolescent social functioning was assessed using UCLA Social Attainment Survey. Assessment of adoptive family functioning was based on Global Family Ratings. Results indicated that dysfunctional family processes and high genetic risk for schizophrenia spectrum disorders contributed approximately equally to adoptees’ adolescent social functioning. Our findings underscore the importance of functional family processes in adolescent social functioning, particularly in individuals at high genetic risk for severe psychiatric disorder.
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