Oncogenic regulatory circuits driven by 19q13 rs11672691 underlies prostate cancer aggressiveness
Xi, Ji-Han; Wei, Gong-Hong (2018-08-20)
Xi, Ji-Han
Wei, Gong-Hong
Informa
20.08.2018
Ji-Han Xia & Gong-Hong Wei (2018) Oncogenic regulatory circuits driven by 19q13 rs11672691 underlies prostate cancer aggressiveness, Molecular & Cellular Oncology, 5:6, DOI: 10.1080/23723556.2018.1516451
https://creativecommons.org/licenses/by-nc-nd/4.0/
© 2018 The Author(s). Taylor & Francis Group, LLC. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
https://creativecommons.org/licenses/by-nc-nd/4.0/
© 2018 The Author(s). Taylor & Francis Group, LLC. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
https://creativecommons.org/licenses/by-nc-nd/4.0/
Julkaisun pysyvä osoite on
https://urn.fi/URN:NBN:fi-fe2019062822338
https://urn.fi/URN:NBN:fi-fe2019062822338
Tiivistelmä
Abstract
The 19q13 allele rs11672691 has been reproducibly found in association with aggressive form of prostate cancer, yet the underlying mechanism remains totally unknown. We have recently uncovered a mechanism by which rs11672691 influenced a novel oncogenic regulatory circuit, including HOXA2, PCAT19 and CEACAM21, thereby contributing to prostate cancer aggressiveness.
Kokoelmat
- Avoin saatavuus [32007]