Delineating Margins of Lentigo Maligna (Melanoma) Using a Hyperspectral Imaging System
Neittaanmäki-Perttu, Noora; Grönroos, Mari; Jeskanen, Leila; Pölönen, Ilkka; Ranki, Annamari; Saksela, Olli; Snellman, Erna (2015)
Neittaanmäki-Perttu, Noora
Grönroos, Mari
Jeskanen, Leila
Pölönen, Ilkka
Ranki, Annamari
Saksela, Olli
Snellman, Erna
2015
Acta Dermato-Venereologica 95 5
549-552
Lääketieteen yksikkö - School of Medicine
Julkaisun pysyvä osoite on
https://urn.fi/URN:NBN:fi:uta-201609272351
https://urn.fi/URN:NBN:fi:uta-201609272351
Tiivistelmä
Lentigo maligna (LM) is an in situ form of melanoma which can progress into invasive lentigo maligna melanoma (LMM). Variations in the pigmentation and thus visibility of the tumour make assessment of lesion borders challenging. We tested hyperspectral imaging system (HIS) in in vivo preoperative delineation of LM and LMM margins. We compared lesion margins delineated by HIS with those estimated clinically, and confirmed histologically. A total of 14 LMs and 5 LMMs in 19 patients were included. HIS analysis matched the histo-pathological analysis in 18/19 (94.7%) cases while in 1/19 (5.3%) cases HIS showed lesion extension not confirmed by histopathology (false positives). Compared to clinical examination, HIS defined lesion borders more accurately in 10/19 (52.6%) of cases (wider, n = 7 or smaller, n = 3) while in 8/19 (42.1%) cases lesion borders were the same as delineated clinically as confirmed histologically. Thus, HIS is useful for the detection of subclinical LM/LMM borders.
Kokoelmat
- Artikkelit [6140]