Number of sons contributes to ageing-associated inflammation
Marttila, Saara; Nevalainen, Tapio; Kananen, Laura; Jylhävä, Juulia; Jylhä, Marja; Hervonen, Antti; Ilonen, Jorma; Hurme, Mikko (2015)
Marttila, Saara
Nevalainen, Tapio
Kananen, Laura
Jylhävä, Juulia
Jylhä, Marja
Hervonen, Antti
Ilonen, Jorma
Hurme, Mikko
2015
Scientific Reports 5
8631
Lääketieteen yksikkö - School of Medicine
Terveystieteiden yksikkö - School of Health Sciences
Julkaisun pysyvä osoite on
https://urn.fi/URN:NBN:fi:uta-201608042133
https://urn.fi/URN:NBN:fi:uta-201608042133
Tiivistelmä
The rate of inflammation increases in elderly individuals, a phenomenon called inflammaging, and is associated with degenerative diseases. However, the causes of inflammaging and the origin of the associated inflammatory mediators have remained enigmatic. We show herein that there is a positive correlation between the number of sons born and C-reactive protein concentrations in 90-year-old women. This association is influenced by HLA genetics known to regulate the immune response against HY antigens.
Kokoelmat
- Artikkelit [6140]