Activities of angiotensin-converting enzymes (ACE1, ACE2) and inhibition by bioactive lactotripeptides (IPP, VPP, LPP) in porcine ocular tissues
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Toxicological and bioactivity evaluation of blackcurrant press cake, sea buckthorn leaves and bark from Scots pine and Norway spruce extracts under a green integrated approach
Pap, Nora; Reshamwala, Dhanik; Korpinen, Risto; Kilpeläinen, Petri; Fidelis, Marina; Furtado, Marianna M.; Sant’Ana, Anderson S.; Wen, Mingchun; Zhang, Liang; Hellström, Jarkko; Marnilla, Pertti; Mattila, Pirjo; Sarjala, Tytti; Yang, Baoru; dos Santos Lima, Amanda; Azevedo, Luciana; Marjomäki, Varpu; Granato, Daniel (Elsevier, 2021)Aqueous extracts from blackcurrant press cake (BC), Norway spruce bark (NS), Scots pine bark (SP), and sea buckthorn leaves (SB) were obtained using maceration and pressurized hot water and tested for their bioactivities. ... -
Enzyme-assisted extraction of anthocyanins and other phenolic compounds from blackcurrant (Ribes nigrum L.) press cake : From processing to bioactivities
Granato, Daniel; Fidelis, Marina; Haapakoski, Marjo; dos Santos Lima, Amanda; Viil, Janeli; Hellström, Jarkko; Rätsep, Reelika; Kaldmäe, Hedi; Bleive, Uko; Azevedo, Luciana; Marjomäki, Varpu; Zharkovsky, Alexander; Pap, Nora (Elsevier Ltd., 2022)The effects of commercial enzymes (pectinases, cellulases, beta-1-3-glucanases, and pectin lyases) on the recovery of anthocyanins and polyphenols from blackcurrant press cake were studied considering two solid:solvent ... -
Salix spp. Bark Hot Water Extracts Show Antiviral, Antibacterial, and Antioxidant Activities : The Bioactive Properties of 16 Clones
Tienaho, Jenni; Reshamwala, Dhanik; Sarjala, Tytti; Kilpeläinen, Petri; Liimatainen, Jaana; Dou, Jinze; Viherä-Aarnio, Anneli; Linnakoski, Riikka; Marjomäki, Varpu; Jyske, Tuula (Frontiers Media SA, 2021)Earlier studies have shown that the bark of Salix L. species (Salicaceae family) is rich in extractives, such as diverse bioactive phenolic compounds. However, we lack knowledge on the bioactive properties of the bark of ... -
Discovery of Potent Indolyl-Hydrazones as Kinase Inhibitors for Breast Cancer : Synthesis, X-ray Single-Crystal Analysis, and In Vitro and In Vivo Anti-Cancer Activity Evaluation
Salama, Eid E.; Youssef, Mohamed F.; Aboelmagd, Ahmed; Boraei, Ahmed T. A.; Nafie, Mohamed S.; Haukka, Matti; Barakat, Assem; Sarhan, Ahmed A. M. (MDPI AG, 2023)According to data provided by the World Health Organization (WHO), a total of 2.3 million women across the globe received a diagnosis of breast cancer in the year 2020, and among these cases, 685,000 resulted in fatalities. ... -
Construction of Spirooxindole Analogues Engrafted with Indole and Pyrazole Scaffolds as Acetylcholinesterase Inhibitors
Islam, Mohammad Shahidul; Al-Majid, Abdullah Mohammed; Azam, Mohammad; Verma, Ved Prakash; Barakat, Assem; Haukka, Matti; Elgazar, Abdullah A.; Mira, Amira; Badria, Farid A. (American Chemical Society (ACS), 2021)Twenty-five new hits of spirooxindole analogs 8a–y engrafted with indole and pyrazole scaffolds were designed and constructed via a [3+2]cycloaddition (32CA) reaction starting from three components: new chalcone-based ...
Ellei toisin mainittu, julkisesti saatavilla olevia JYX-metatietoja (poislukien tiivistelmät) saa vapaasti uudelleenkäyttää CC0-lisenssillä.