Understanding biomaterial-tissue interface quality: combined in vitro evaluation

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Journal Title
Journal ISSN
Volume Title
A2 Katsausartikkeli tieteellisessä aikakauslehdessä
Date
2017-01-01
Major/Subject
Mcode
Degree programme
Language
en
Pages
13
550-562
Series
SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS, Volume 18, issue 1
Abstract
One of the greatest challenges in the development of new medical products and devices remains in providing maximal patient safety, efficacy and suitability for the purpose. A ‘good quality’ of the tissue-implant interface is one of the most critical factors for the success of the implant integration. In this paper this challenge is being discussed from the point of view of basic stimuli combination to experimental testing. The focus is in particular on bacterial effects on tissue-implant interaction (for different materials). The demonstration of the experimental evaluation of the tissue-implant interface is for dental abutment with mucosal contact. This shows that testing of the interface quality could be the most relevant in controlled conditions, which mimic as possible the clinical applications, but consider variables being under the control of the evaluator.
Description
Keywords
Biomaterial, biomechanics, dynamics, implant, in vitro, simulation, testing
Other note
Citation
Gasik, M 2017, ' Understanding biomaterial-tissue interface quality : combined in vitro evaluation ', SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS, vol. 18, no. 1, pp. 550-562 . https://doi.org/10.1080/14686996.2017.1348872